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Dean A Jobe Selected Research

1-oleoyl-2-stearoylphosphatidylcholine

7/2015Antibody responses to Borrelia burgdorferi outer surface proteins C and F in experimentally infected Beagle dogs.
6/2011Rapid decline of OspC borreliacidal antibodies following treatment of patients with early Lyme disease.
2/2009Bacterin that induces anti-OspA and anti-OspC borreliacidal antibodies provides a high level of protection against canine Lyme disease.
6/2008Significantly improved accuracy of diagnosis of early Lyme disease by peptide enzyme-linked immunosorbent assay based on the borreliacidal antibody epitope of Borrelia burgdorferi OspC.
5/2007Borreliacidal OspC antibody response of canines with Lyme disease differs significantly from that of humans with Lyme disease.
6/2005Borreliacidal OspC antibodies specific for a highly conserved epitope are immunodominant in human lyme disease and do not occur in mice or hamsters.
7/2003C-terminal region of outer surface protein C binds borreliacidal antibodies in sera from patients with Lyme disease.

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Dean A Jobe Research Topics

Disease

13Lyme Disease (Disease, Lyme)
10/2021 - 07/2002
8Infections
05/2020 - 07/2002
2Erythema
10/2021 - 01/2016
1Paralysis (Palsy)
10/2021
1Arthritis (Polyarthritis)
10/2021
1Tick-Borne Diseases (Tick-Borne Disease)
11/2019
1Melanoma (Melanoma, Malignant)
12/2013

Drug/Important Bio-Agent (IBA)

11AntibodiesIBA
10/2021 - 07/2002
71-oleoyl-2-stearoylphosphatidylcholineIBA
07/2015 - 07/2003
5Immunoglobulin G (IgG)IBA
05/2020 - 07/2003
4Peptides (Polypeptides)IBA
10/2021 - 06/2008
4Immunoglobulin M (IgM)IBA
05/2020 - 07/2003
3ImmunosorbentsIBA
10/2021 - 06/2008
3AntigensIBA
10/2021 - 06/2008
3EnzymesIBA
10/2021 - 06/2008
3Bacterial VaccinesIBA
05/2020 - 02/2009
3Amino AcidsFDA Link
06/2008 - 06/2005
2EpitopesIBA
06/2008 - 06/2005
2OspC proteinIBA
06/2005 - 07/2003
1InterferonsIBA
10/2021
1DecorinIBA
05/2020
14,5-dibromo-2-pyrrolic acidIBA
05/2020
1Carrier Proteins (Binding Protein)IBA
05/2020
1Immune Sera (Antisera)IBA
05/2020
1tributyl phosphate (TBP)IBA
11/2019
1Anti-Bacterial Agents (Antibiotics)IBA
01/2016
1Interferon-gamma (Interferon, gamma)IBA
01/2016
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
12/2013
1Proteins (Proteins, Gene)FDA Link
11/2004
1Complement System Proteins (Complement)IBA
11/2004

Therapy/Procedure

2Therapeutics
10/2021 - 01/2016
1Aftercare (After-Treatment)
10/2021